| ID | DRAMP03937 |
|---|---|
| Sequence | GSKKPVPIIYCNRRTGKC |
| Length | 18 |
| Name | G18C (truncated isoform of thanatin, residue 1-18) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Antifungal |
| Pathogen | Gram-positive bacteria: Aerococcus viridans (MIC=2.5-5 µM), Micrococcus luteus (MIC=1.2-2.5 µM), Bacillus megaterium (MIC=5-10 µM), Bacillus subtilis (MIC=5-10 µM), Pediococcus acidilactici (MIC=20-40 µM).##Fungi: Neurospora crassa (MIC=10-20 µM), Botrytis cinerea (MIC=5-10 µM), Nectria haematococca (MIC=5-10 µM), Trichoderma viride (MIC=20-40 µM), Alternaria brassicicola (MIC=5-10 µM), Fusarium culmorum (MIC=10-20 µM), A. pisi (MIC=20-40 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8577744 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | GSKKPVPIIYCNRRTGKC |
| Molecular Weight | 2020.426 |
| Grand Average of Hydropathy | -0.711 |
| Isoelectric Point | 10.061 |
| Charge at pH 7.4 | 4.498 |
| Secondary Structure | Helix: 0.222, Turn: 0.333, Sheet: 0.000 |
| Instability Index | 49.044 |
| Aromaticity | 0.056 |