Basic Information
| ID | DRAMP03967 |
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| Sequence | KWKLFKKIPKFLHLAKKF |
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| Length | 18 |
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| Name | P18 (Cecropin A(1-8)-Magainin 2(1−12) hybrid peptide analogue) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antitumor |
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| Pathogen | Gram-negative bacteria: Escherichia coli KCTC 1682 (MIC=6.25 µM), Pseudomonas aeruginosa KCTC 1637 (MIC=1.56 µM), Proteus vulgaris (MIC=3.125 µM).##Gram-positive bacteria: Bacillus subtilis KCTC 1918 (MIC=0.78 µM), Staphylococcus aureus KCTC 1621 (MIC=1.56 µM), Bacillus megaterium KCTC 1096 (MIC=0.78 µM).##Tumor cells: MDA-MB-361 (IC50=8.0 µM), Jurkat (IC50=4.0 µM), K-562 (IC50=3.5 µM), Normal cells NIH 3T3 (IC50=75.0 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 12005420, 12370027 |
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