| ID | DRAMP03998 |
|---|---|
| Sequence | RKKWFW |
| Length | 6 |
| Name | PAF26 (Trp-rich; combinatorial library) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Antifungal |
| Pathogen | [Ref.11976121] Gram-negative bacterium: Escherichia coli DH5α (MIC=160 µM, IC50>80 µM);##Fungi: Penicillium digitatum PHI-26 (MIC=20 µM, IC50=11 ± 1 µM), Penicillium italicum PHI-1 (MIC=40 µM, IC50=22 ± 3 µM), Botrytis cinerea CECT2100 (MIC=60 µM, IC50=38 ± 24 µM), Fusarium oxysporum CECT2866 (MIC=80 µM, IC50=45 ± 4 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11976121 |
Physicochemical Properties
| Residues | 6 |
|---|---|
| Sequence | RKKWFW |
| Molecular Weight | 950.139 |
| Grand Average of Hydropathy | -1.883 |
| Isoelectric Point | 11.166 |
| Charge at pH 7.4 | 2.552 |
| Secondary Structure | Helix: 0.500, Turn: 0.000, Sheet: 0.000 |
| Instability Index | 8.333 |
| Aromaticity | 0.5 |
