Basic Information

IDDRAMP03998
SequenceRKKWFW
Length6
NamePAF26 (Trp-rich; combinatorial library)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Antifungal
Pathogen[Ref.11976121] Gram-negative bacterium: Escherichia coli DH5α (MIC=160 µM, IC50>80 µM);##Fungi: Penicillium digitatum PHI-26 (MIC=20 µM, IC50=11 ± 1 µM), Penicillium italicum PHI-1 (MIC=40 µM, IC50=22 ± 3 µM), Botrytis cinerea CECT2100 (MIC=60 µM, IC50=38 ± 24 µM), Fusarium oxysporum CECT2866 (MIC=80 µM, IC50=45 ± 4 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11976121

Physicochemical Properties

Residues6
SequenceRKKWFW
Molecular Weight950.139
Grand Average of Hydropathy-1.883
Isoelectric Point11.166
Charge at pH 7.42.552
Secondary StructureHelix: 0.500, Turn: 0.000, Sheet: 0.000
Instability Index8.333
Aromaticity0.5

Similar Structure Search

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