| ID | DRAMP04005 |
|---|---|
| Sequence | VSLFPVSLFP |
| Length | 10 |
| Name | Gramicidin analogue ([Ser2,2']-GS) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacteria: Streptococcus pyogenes N.Y.5 (MIC=25 µg/ml), Myotis flavus ATCC 10240 (MIC=12.5 µg/ml);##Gram-negative bacteria: Corynebacterium diphtheriae P.W.8 (MIC=12.5 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8791160 |
Physicochemical Properties
| Residues | 10 |
|---|---|
| Sequence | VSLFPVSLFP |
| Molecular Weight | 1105.325 |
| Grand Average of Hydropathy | 1.68 |
| Isoelectric Point | 5.495 |
| Charge at pH 7.4 | -0.477 |
| Secondary Structure | Helix: 0.600, Turn: 0.400, Sheet: 0.200 |
| Instability Index | 66.78 |
| Aromaticity | 0.2 |