Basic Information

IDDRAMP04051
SequenceRICRIVVIRCIR
Length12
NameBac2I-NH2 (cyclic derivative of bactenecin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli K-12 (MIC=4 µg/ml), Pseudomonas aeruginosa K799 (MIC=16 µg/ml), Salmonella typhimurium 14028s (MIC=8 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=32 µg/ml), Staphylococcus epidermidis C621 (MIC=8 µg/ml), Enterococcus faecalis ATCC 29212 (MIC>32 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10223951

Physicochemical Properties

Residues12
SequenceRICRIVVIRCIR
Molecular Weight1499.936
Grand Average of Hydropathy1.117
Isoelectric Point11.526
Charge at pH 7.43.508
Secondary StructureHelix: 0.500, Turn: 0.000, Sheet: 0.000
Instability Index2.092
Aromaticity0

Similar Structure Search

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