Basic Information

IDDRAMP04052
SequenceRLCPRVRIRVCR
Length12
NameBacP2R-NH2 (cyclic derivative of bactenecin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli K-12 (MIC=4 µg/ml), Pseudomonas aeruginosa K799 (MIC=16 µg/ml), Salmonella typhimurium 14028s (MIC=32 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC>32 µg/ml), Staphylococcus epidermidis C621 (MIC=16 µg/ml), Enterococcus faecalis ATCC 29212 (MIC>32 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10223951

Physicochemical Properties

Residues12
SequenceRLCPRVRIRVCR
Molecular Weight1526.922
Grand Average of Hydropathy-0.2
Isoelectric Point11.825
Charge at pH 7.44.508
Secondary StructureHelix: 0.333, Turn: 0.083, Sheet: 0.083
Instability Index18.933
Aromaticity0

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