| ID | DRAMP04070 |
|---|---|
| Sequence | CWKWKWKWGSGWKWKWKWC |
| Length | 19 |
| Name | Cyclic cationic V7 peptide |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
| Pathogen | [Ref.15328096]Gram-negative bacteria: Escherichia coli ATTC 25922 (MIC=114 nM), Pseudomonas aeruginosa ATTC 27853 (MIC=4 nM), Klebsiella pneumoniae ATTC 13883 (MIC=458 nM), Salmonella enterica serovar Typhimurium ATTC 14028 (MIC=4 nM), Shigella sonnei ATTC 25931 (MIC=7 nM). |
| Hemolytic Activity | [Ref.15328096]EC50=45000 nM against human erythrocytes |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 15328096 |
Physicochemical Properties
| Residues | 19 |
|---|---|
| Sequence | CWKWKWKWGSGWKWKWKWC |
| Molecular Weight | 2684.194 |
| Grand Average of Hydropathy | -1.432 |
| Isoelectric Point | 10.048 |
| Charge at pH 7.4 | 5.493 |
| Secondary Structure | Helix: 0.421, Turn: 0.158, Sheet: 0.000 |
| Instability Index | 22.974 |
| Aromaticity | 0.421 |