Basic Information

IDDRAMP04115
SequenceKWKSFIKKLTKKFLHSAKKF
Length20
NameK11 (derivative of CP-P)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus CMCC26003 (MIC=0.5 µg/mL), Bacillus subtilis DB430 (MIC=2 µg/mL), Bacillus pumilus CMCC63202 (MIC=0.5 µg/mL), Soluble wall Micrococcus S1.634 (MIC=1 µg/mL), Micrococcus luteus CMCC28001 (MIC=2 µg/mL).##Gram-negative bacteria: E. coli ATCC8099 (MIC=0.5 µg/mL), Klebsiella pneumoniae CMCC46117 (MIC=2 µg/mL), Salmonella paratyphi BCMCC50094 (MIC=2 µg/mL), Pseudomonas aeruginosa CMCC10104 (MIC=4 µg/mL).##Clinical isolates: Acinetobacter baumannii b-01 (MIC=0.8 µg/mL), Acinetobacter baumannii b-02 (MIC=3.125 µg/mL), Acinetobacter baumannii b-03 (MIC=3.25 µg/mL), Acinetobacter baumannii b-04 (MIC=1.6 µg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22518150

Physicochemical Properties

Residues20
SequenceKWKSFIKKLTKKFLHSAKKF
Molecular Weight2494.074
Grand Average of Hydropathy-0.765
Isoelectric Point10.845
Charge at pH 7.47.574
Secondary StructureHelix: 0.350, Turn: 0.100, Sheet: 0.150
Instability Index1.01
Aromaticity0.2

Similar Structure Search

Candidates based on structure

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