| ID | DRAMP04115 |
|---|---|
| Sequence | KWKSFIKKLTKKFLHSAKKF |
| Length | 20 |
| Name | K11 (derivative of CP-P) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus CMCC26003 (MIC=0.5 µg/mL), Bacillus subtilis DB430 (MIC=2 µg/mL), Bacillus pumilus CMCC63202 (MIC=0.5 µg/mL), Soluble wall Micrococcus S1.634 (MIC=1 µg/mL), Micrococcus luteus CMCC28001 (MIC=2 µg/mL).##Gram-negative bacteria: E. coli ATCC8099 (MIC=0.5 µg/mL), Klebsiella pneumoniae CMCC46117 (MIC=2 µg/mL), Salmonella paratyphi BCMCC50094 (MIC=2 µg/mL), Pseudomonas aeruginosa CMCC10104 (MIC=4 µg/mL).##Clinical isolates: Acinetobacter baumannii b-01 (MIC=0.8 µg/mL), Acinetobacter baumannii b-02 (MIC=3.125 µg/mL), Acinetobacter baumannii b-03 (MIC=3.25 µg/mL), Acinetobacter baumannii b-04 (MIC=1.6 µg/mL). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22518150 |
Physicochemical Properties
| Residues | 20 |
|---|---|
| Sequence | KWKSFIKKLTKKFLHSAKKF |
| Molecular Weight | 2494.074 |
| Grand Average of Hydropathy | -0.765 |
| Isoelectric Point | 10.845 |
| Charge at pH 7.4 | 7.574 |
| Secondary Structure | Helix: 0.350, Turn: 0.100, Sheet: 0.150 |
| Instability Index | 1.01 |
| Aromaticity | 0.2 |
