Basic Information

IDDRAMP04700
SequenceDLWQFGKMILKVAGKLPFPYYGAYGCYCGWGGRGKPKDPTDRCCFVHDCC
Length50
NameBasic phospholipase A2 BnpTX-1 (BnPTx-I, svPLA2; Phosphatidylcholine 2-acylhydrolase)
SourceBothrops pauloensis (Neuwied's lancehead) (Bothrops neuwiedipauloensis)
ActivityAntimicrobial, Antibacterial, Antiparasitic, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: E. coli ATCC29648 and Gram-positive bacterium: S. aureus ATCC 25923.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0DM51
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15302537

Physicochemical Properties

Residues50
SequenceDLWQFGKMILKVAGKLPFPYYGAYGCYCGWGGRGKPKDPTDRCCFVHDCC
Molecular Weight5652.577
Grand Average of Hydropathy-0.266
Isoelectric Point8.606
Charge at pH 7.42.426
Secondary StructureHelix: 0.300, Turn: 0.240, Sheet: 0.120
Instability Index20.29
Aromaticity0.18

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Candidates based on structure

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