Basic Information

IDDRAMP18213
SequenceVKLFPVKLFP
Length10
NameGramicidin S(Bacteriocin)
SourceBacillus brevis
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive, Gram-negative (broad-spectrum)
Hemolytic ActivityIt exhibits hemolytic activity at 25 μM and 45 μM against human red cells and sheep red cells.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationNo specific N-terminal
C-terminal ModificationNo specific C-terminal
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8836773, 24388950

Physicochemical Properties

Residues10
SequenceVKLFPVKLFP
Molecular Weight1187.515
Grand Average of Hydropathy1.06
Isoelectric Point10.002
Charge at pH 7.41.518
Secondary StructureHelix: 0.600, Turn: 0.200, Sheet: 0.200
Instability Index44.04
Aromaticity0.2

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.