| ID | DRAMP18386 |
|---|---|
| Sequence | SPKKTKPVKPKKVA |
| Length | 14 |
| Name | VK25 (histone derived; reptiles; animals) |
| Source | blood plasma, Komodo dragon, Varanus komodoensis |
| Activity | Antimicrobial, Antibacterial |
| Pathogen | Active against P. eruginosa ATCC9027 (EC50 3.2 uM) and S. aureus ATCC 25923 (EC50 2.5 uM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | [Ref.28164707]No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 28164707 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | SPKKTKPVKPKKVA |
| Molecular Weight | 1535.916 |
| Grand Average of Hydropathy | -1.393 |
| Isoelectric Point | 10.699 |
| Charge at pH 7.4 | 5.238 |
| Secondary Structure | Helix: 0.143, Turn: 0.286, Sheet: 0.071 |
| Instability Index | 35.536 |
| Aromaticity | 0 |