| ID | DRAMP18389 |
|---|---|
| Sequence | AKKPVAKKAAGGVKKPKK |
| Length | 18 |
| Name | VK12 (histone derived; animals) |
| Source | blood plasma, Komodo dragon, Varanus komodoensis |
| Activity | Antimicrobial, Antibacterial |
| Pathogen | Active against P. eruginosa ATCC9027 (EC50 0.7 uM) and S. aureus ATCC 25923 (EC50 0.8 uM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | [Ref.28164707]No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 28164707 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | AKKPVAKKAAGGVKKPKK |
| Molecular Weight | 1834.3 |
| Grand Average of Hydropathy | -1.089 |
| Isoelectric Point | 10.845 |
| Charge at pH 7.4 | 7.588 |
| Secondary Structure | Helix: 0.111, Turn: 0.222, Sheet: 0.222 |
| Instability Index | 17.022 |
| Aromaticity | 0 |