| ID | DRAMP18499 |
|---|---|
| Sequence | WKSYVRRWRSR |
| Length | 11 |
| Name | TSG-8 (Ixosin-B peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.23570790]Gram-positive bacteria: Staphylococcus aureus (MIC=32 μM);##Gram-negative bacteria: Escherichia coli (MIC=16 μM), Pseudomonas aeruginosa (MIC>100 μM) |
| Hemolytic Activity | [Ref.23570790]-1.2±2.6% hemolysis at 100μM against human red blood cells. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23570790 |
Physicochemical Properties
| Residues | 11 |
|---|---|
| Sequence | WKSYVRRWRSR |
| Molecular Weight | 1579.809 |
| Grand Average of Hydropathy | -2.036 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 4.552 |
| Secondary Structure | Helix: 0.364, Turn: 0.182, Sheet: 0.000 |
| Instability Index | 170.691 |
| Aromaticity | 0.273 |