Basic Information

IDDRAMP18502
SequenceWKSYVRRWR
Length9
NameTSG-10 (Ixosin-B peptide derivative)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.23570790]Gram-positive bacteria: Staphylococcus aureus (MIC=64 μM);##Gram-negative bacteria: Escherichia coli (MIC=64 μM), Pseudomonas aeruginosa (MIC>100 μM)
Hemolytic Activity[Ref.23570790]1.1±1.3% hemolysis at 100μM against human red blood cells.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23570790

Physicochemical Properties

Residues9
SequenceWKSYVRRWR
Molecular Weight1336.546
Grand Average of Hydropathy-1.9
Isoelectric Point11.723
Charge at pH 7.43.552
Secondary StructureHelix: 0.444, Turn: 0.111, Sheet: 0.000
Instability Index136.178
Aromaticity0.333

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.