Basic Information

IDDRAMP18507
SequenceFSGGNCRGFRRRCFCTK
Length17
NameSolyC (Plant defensin; tomato, plants)
SourceTomato
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.23124812]Gram-positive bacteria: Staphylococcus aureus A170 (MIC=40 μg/mL), Staphylococcus epidermidis (MIC=40 μg/mL), Listeria monocytogenes (MIC=40 μg/mL);##Gram-negative bacteria: Salmonella enterica serovar Paratyphi (MIC=15 μg/mL), Escherichia coli (MIC=15 μg/mL), Helicobacter pylori VB1 (MIC=15 μg/mL), Helicobacter pylori VB2 (MIC=10 μg/mL), Helicobacter pylori VB3 (MIC=15 μg/mL), Helicobacter pylori VB4 (MIC=12 μg/mL), Helicobacter pylori VB5 (MIC=15 μg/mL), Helicobacter pylori VB6 (MIC=10 μg/mL), Helicobacter pylori VB7 (MIC=15 μg/mL), Helicobacter pylori VB8 (MIC=10 μg/mL), Helicobacter pylori VB9 (MIC=10 μg/mL), Helicobacter pylori VB10 (MIC=15 μg/mL).
Hemolytic Activity[Ref.23124812]<5% hemolysis at 50 μg/mL against mouse red blood cells.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23124812

Physicochemical Properties

Residues17
SequenceFSGGNCRGFRRRCFCTK
Molecular Weight1995.318
Grand Average of Hydropathy-0.718
Isoelectric Point10.74
Charge at pH 7.44.481
Secondary StructureHelix: 0.176, Turn: 0.294, Sheet: 0.000
Instability Index91.553
Aromaticity0.176

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Candidates based on structure

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