| ID | DRAMP18508 |
|---|---|
| Sequence | KFAKKFKWFAKAAFKFFKK |
| Length | 19 |
| Name | gp41w-FKA (gp41 peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.23019445]Gram-positive bacterium: Staphylococcus aureus (MIC<10 μg/ml, MBC=20-30 μg/ml);##Gram-negative bacterium: Escherichia coli (MIC=10-30 μg/ml, MBC=40-50 μg/ml) |
| Hemolytic Activity | [Ref.23019445]EC50=195 μg/mL against human red blood cells. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23019445 |
Physicochemical Properties
| Residues | 19 |
|---|---|
| Sequence | KFAKKFKWFAKAAFKFFKK |
| Molecular Weight | 2396.958 |
| Grand Average of Hydropathy | -0.426 |
| Isoelectric Point | 10.845 |
| Charge at pH 7.4 | 7.537 |
| Secondary Structure | Helix: 0.368, Turn: 0.000, Sheet: 0.211 |
| Instability Index | -14.258 |
| Aromaticity | 0.368 |