| ID | DRAMP18572 |
|---|---|
| Sequence | VNSKKISPKSIKVSK |
| Length | 15 |
| Name | LL-IIIs-6a (lasioglossin III peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.22526241]Gram-positive bacteria: Micrococcus luteus (MIC=1 μM), Bacillus cereus (MIC=1.1 μM), Staphylococcus aureus (MIC=93 μM);##Gram-negative bacteria: Escherichia coli (MIC=7.8 μM), Pseudomonas aeruginosa (MIC=93 μM). |
| Hemolytic Activity | [Ref.22526241]LC50>100 μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22526241 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | VNSKKISPKSIKVSK |
| Molecular Weight | 1642.981 |
| Grand Average of Hydropathy | -0.693 |
| Isoelectric Point | 10.602 |
| Charge at pH 7.4 | 4.511 |
| Secondary Structure | Helix: 0.267, Turn: 0.400, Sheet: 0.000 |
| Instability Index | 21.647 |
| Aromaticity | 0 |