| ID | DRAMP18597 |
|---|---|
| Sequence | VNWKKVLAKIIKVAK |
| Length | 15 |
| Name | LL-I/2 (Lasioglossin LL-I peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.19591185]Gram-positive bacteria: Bacillus subtilis (MIC=0.6 μM), Staphylococcus aureus (MIC=7.2 μM);##Gram-negative bacteria: Escherichia coli (MIC=0.7 μM), Pseudomonas aeruginosa (MIC=26.9 μM). |
| Hemolytic Activity | [Ref.19591185]LC50>200 μM against rat red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 19591185 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | VNWKKVLAKIIKVAK |
| Molecular Weight | 1738.211 |
| Grand Average of Hydropathy | 0.34 |
| Isoelectric Point | 10.602 |
| Charge at pH 7.4 | 4.511 |
| Secondary Structure | Helix: 0.467, Turn: 0.067, Sheet: 0.200 |
| Instability Index | -20.22 |
| Aromaticity | 0.067 |