Basic Information

IDDRAMP18671
SequenceKCRRRKVHGPMIRIRKK
Length17
NameTO17 (TFPI-1 C-terminal peptide)
SourceRed drum (Sciaenops ocellatus)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.29183811] Gram-positive bacteria: Micrococcus luteus (MIC=9 μM; MBC=18 μM), Staphylococcus aureus (MIC=4 μM; MBC=8 μM);##Gram-negative bacterium: Vibrio vulnificus (MIC= 80 μM; MBC=80 μM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29183811

Physicochemical Properties

Residues17
SequenceKCRRRKVHGPMIRIRKK
Molecular Weight2162.724
Grand Average of Hydropathy-1.512
Isoelectric Point12
Charge at pH 7.48.559
Secondary StructureHelix: 0.176, Turn: 0.118, Sheet: 0.059
Instability Index61.271
Aromaticity0

Similar Structure Search

Candidates based on structure

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