Basic Information

IDDRAMP18720
SequenceGADDDDD
Length7
NameSAAP fraction 6 (Surfactant-associated anionic peptides; Asp-rich; sheep, ruminant, mammals, animals)
SourceOvis aries
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.8552650] Gram-negative bacterium: Pasteurella haemolytica (MBC50=0.02 mM in Zn-saline, MBC50=10.10 mM in Test buffer; Peptide/surfactant mixture MBC50=0.04 mM in Zn-saline, MBC50=5.18 mM in Test buffer; Peptide/serum mixture MBC50=0.04 mM in Zn-saline, MBC50=5.59 mM in Test buffer; Peptide/surfactant/serum mixture MBC50=0.04 mM in Zn-saline, MBC50=4.75 mM in Test buffer).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8552650

Physicochemical Properties

Residues7
SequenceGADDDDD
Molecular Weight721.582
Grand Average of Hydropathy-2.3
Isoelectric Point4.05
Charge at pH 7.4-5.439
Secondary StructureHelix: 0.000, Turn: 0.143, Sheet: 0.143
Instability Index-15.686
Aromaticity0

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