Basic Information
| ID | DRAMP20800 |
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| Sequence | KKKKPLFGLFFGLF |
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| Length | 14 |
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| Name | the K4 peptide (synthetic; Phe-rich >25%) |
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| Source | the APD database-aided design. |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
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| Pathogen | [Ref.19573572] Gram-negative bacteria: Escherichia coli (MIC=40-80 μg/ml or 24-48 μM), Vibrio alginolyticus (MIC=10-20 μg/ml or 6-12 μM), Vibrio harveyi (MIC=5-10 μg/ml or 3-6 μM). |
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| Hemolytic Activity | [Ref.19573572] No significant hemolytic activity is observed at 10 and 40 μg/ml. Slight hemolysis (6.65%) is shown at 160 μg/ml. |
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| Cytotoxicity | [Ref.19573572] The cell viability of CHO-K1 cells is 127%, 123%,78% and 10% at peptide concentrations of 10 μg/ml, 40 μg/ml, 160 μg/ml and 640 μg/ml |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 19573572 |
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