Basic Information

IDDRAMP20825
SequenceKIKKGFKKIFKRLPPIGVGVSIPLAGKR
Length28
NameAM-CATH28
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.28089718] Gram-negative bacteria:Acinetobacter baumannii ATCC 9955 (MIC=28μg/ml), Acinetobacter baumannii ATCC BAA-1794 (MIC=10μg/ml), K. pneumoniae ATCC 33495 (MIC=5.6μg/ml), K. pneumoniae ATCC BAA-1705 (MIC=28μg/ml), Pseudomonas aeruginosa ATCC 9027 (MIC=21μg/ml)
Hemolytic Activity[Ref.28089718] 1% hemolysis at 300μg/ml against sheep red cells
Cytotoxicity[Ref.28089718] The survival rate of A549 human lung epithelial cells is 122% at a peptide concentration of 300 μg/ml
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID28089718

Physicochemical Properties

Residues28
SequenceKIKKGFKKIFKRLPPIGVGVSIPLAGKR
Molecular Weight3076.854
Grand Average of Hydropathy-0.075
Isoelectric Point12
Charge at pH 7.48.54
Secondary StructureHelix: 0.357, Turn: 0.286, Sheet: 0.107
Instability Index16.729
Aromaticity0.071

Similar Structure Search

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