| ID | DRAMP20851 |
|---|---|
| Sequence | VWRRWRRFWRR |
| Length | 11 |
| Name | [R4,R10]C1b(3-13) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.27060618]Gram-negative bacteria:Escherichia coli(MIC=3.13μM);Pseudomonas aeruginosa(MIC=3.13μM);##Gram-positive bacteria:Staphylococcus aureus(MIC= 3.13μM);B. cereus(MIC=3.13μM);S. lactis(MIC=3.13μM);E. faecalis (MIC=1.56μM);E. faecium(MIC=1.56μM) |
| Hemolytic Activity | [Ref.27060618] HC50>500μM against human red blood cells |
| Cytotoxicity | [Ref.27060618] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 27060618 |
Physicochemical Properties
| Residues | 11 |
|---|---|
| Sequence | VWRRWRRFWRR |
| Molecular Weight | 1760.064 |
| Grand Average of Hydropathy | -2.064 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 5.523 |
| Secondary Structure | Helix: 0.455, Turn: 0.000, Sheet: 0.000 |
| Instability Index | 217.382 |
| Aromaticity | 0.364 |