Basic Information

IDDRAMP20872
SequenceGLLKRI
Length6
NamePal-ano-6 (Pal-anoplin peptide derivative)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=0.61 μg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.25 μg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=1.63 μg/mL).
Hemolytic Activity[Ref.29614317] HC50=7.51μg/mL against human red blood cells
Cytotoxicity[Ref.29614320] No cytotoxicity information found
N-terminal ModificationAcylation (Gly1 conjugated with a palmitoyl group)
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29614317

Physicochemical Properties

Residues6
SequenceGLLKRI
Molecular Weight698.897
Grand Average of Hydropathy0.55
Isoelectric Point11.001
Charge at pH 7.41.555
Secondary StructureHelix: 0.500, Turn: 0.167, Sheet: 0.333
Instability Index48.517
Aromaticity0

Similar Structure Search

Candidates based on structure

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