| ID | DRAMP20930 |
|---|---|
| Sequence | KKLFKKILKYLA |
| Length | 12 |
| Name | BP100-Ala-NH-C16H33 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.29750913] Gram-negative bacteria:Escherichia coli(ATCC 25922)(MIC=16μM);##Gram-positive bacteria:Staphylococcus aureus (ATCC 25923)(MIC=8μM);Bacillus subtilis(PY79)(MIC=8μM) |
| Hemolytic Activity | [Ref.29750913] C50 =6.3μM against human red blood cells |
| Cytotoxicity | [Ref.29750913] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation and Acylation (-NH-C₁₆H₃₃, conjugated with a n‑hexadecyl acyl chain) |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 29750913 |
Physicochemical Properties
| Residues | 12 |
|---|---|
| Sequence | KKLFKKILKYLA |
| Molecular Weight | 1492.932 |
| Grand Average of Hydropathy | -0.025 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 4.542 |
| Secondary Structure | Helix: 0.500, Turn: 0.000, Sheet: 0.333 |
| Instability Index | -8.533 |
| Aromaticity | 0.167 |