Basic Information
| ID | DRAMP21040 |
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| Sequence | WGRRGWGaGRRYVRW |
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| Length | 15 |
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| Name | analog 3 (Derived from Ib-AMP2) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.19778562] Gram-positive bacteria : Bacillus subtilis(KCTC 3068)(MIC=4 μM), Staphylococcus epidermidis(KCTC 1917)(MIC=8 μM), Staphylococcus aureus(KCTC 1621)(MIC=4 μM), Staphylococcus aureus (MRSA)(CCARM 3543)(MIC=2 μM);##Gram-negative bacteria : Escherichia coli(KCTC 1682)(MIC=16 μM), Pseudomonas aeruginosa(KCTC 1637)(MIC=16 μM), Salmonella typhimurium(KCTC 1926)(MIC=4 μM), Pseudomonas aeruginosa (MDRPA)(CCARM 2095)(MIC=16 μM) |
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| Hemolytic Activity | [Ref.19778562] MHC>400 [Ref.19778562] MHC>400 μM against human red blood cells |
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| Cytotoxicity | [Ref.19778562] No cytotoxicity information found. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 19778562 |
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