Basic Information
| ID | DRAMP21136 |
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| Sequence | HRWWRWWRH |
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| Length | 9 |
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| Name | P8 (Derived from P5) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.28372989] Gram-positive bacteria : Bacillus subtilis(MIC=1 μM, MBC=1 μM), Staphylococcus aureus(MIC=16 μM, MBC=32 μM);##Gram-negative bacteria : Escherichia coli(MIC=8 μM, MBC=32 μM) |
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| Hemolytic Activity | [Ref.28372989] MHC5=86.67 μM against human red blood cells |
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| Cytotoxicity | [Ref.28372989] IC50 > 86.67 μM for hPBMCs. The cell viability of hPBMCs is 96%, 98.4%, 86.8%, 84.8% and 88.8% and at peptide concentrations of 0.33, 0.67, 6.67, 12.33 and 86.67 μM. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 28372989 |
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