Basic Information

IDDRAMP21179
SequenceGILSSLWKKPKKIIAK
Length16
NameHYL-26 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC>100 μM), Staphylococcus epidermidis(MIC>100 μM);##Gram-negative bacteria : Escherichia coli(MIC>100μM), Pseudomonas aeruginosa 5482(MIC=98 μM);##Fungi : Candida albicans(MIC>100 μM)
Hemolytic Activity[Ref.26998557] LC50>400 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGILSSLWKKPKKIIAK
Molecular Weight1810.274
Grand Average of Hydropathy-0.069
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.375, Turn: 0.250, Sheet: 0.188
Instability Index32.925
Aromaticity0.062

Similar Structure Search

Candidates based on structure

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