Basic Information
| ID | DRAMP21213 |
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| Sequence | irikirik |
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| Length | 8 |
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| Name | IK8-all D (Derived from IK8-all L) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=2.0 mg/L), Staphylococcus aureus(MIC=3.9 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=3.9 mg/L), Pseudomonas aeruginosa(MIC=7.8 mg/L);##Fungi : Candida albicans(MIC=3.9 mg/L) |
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| Hemolytic Activity | [Ref.24211081] HC10=1750 mg/L against rabbit red blood cells |
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| Cytotoxicity | [Ref.24211081] The cell viability of mouse alveolar macrophage RAW264.7 cells is 100%, 100%, 95%, 90%, 83.8%, 86.2%, 50%, 8.8% and 5% at peptide concentrations of 1, 2, 4, 8, 16, 31, 62, 100 and 125 mg/L. ##The cell viability of human fetatl lung fibrobl |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 24211081 |
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