Basic Information

IDDRAMP21216
SequenceIrIkIrIk
Length8
NameIK8-4D (Derived from IK8-all L)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC>500 mg/L), Staphylococcus aureus(MIC>500 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>500 mg/L), Pseudomonas aeruginosa(MIC>500 mg/L);##Fungi : Candida albicans(MIC>500 mg/L)
Hemolytic Activity[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells
Cytotoxicity[Ref.24211081] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID24211081

Physicochemical Properties

Residues8
SequenceIrIkIrIk
Molecular Weight1039.362
Grand Average of Hydropathy0.15
Isoelectric Point12
Charge at pH 7.43.552
Secondary StructureHelix: 0.500, Turn: 0.000, Sheet: 0.000
Instability Index-23.087
Aromaticity0

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