| ID | DRAMP21269 |
|---|---|
| Sequence | LKKLLKLAKKLLKLAG |
| Length | 16 |
| Name | LK-L8A (Derived from LK) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.23894079] Gram-positive bacteria : Staphylococcus aureus (ATCC 29213)(MIC=5 μM);##Gram-negative bacteria : Escherichia coli (ATCC 25922)(MIC=5 μM) |
| Hemolytic Activity | [Ref.23894079] MHC10=1.25 μM against human red blood cells |
| Cytotoxicity | [Ref.23894079] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23894079 |
Physicochemical Properties
| Residues | 16 |
|---|---|
| Sequence | LKKLLKLAKKLLKLAG |
| Molecular Weight | 1778.359 |
| Grand Average of Hydropathy | 0.4 |
| Isoelectric Point | 10.699 |
| Charge at pH 7.4 | 5.542 |
| Secondary Structure | Helix: 0.438, Turn: 0.062, Sheet: 0.562 |
| Instability Index | -27.769 |
| Aromaticity | 0 |