Basic Information

IDDRAMP21291
SequenceFKRQVQRIKDFLR
Length13
NameLt-I4Q (Derived from Lt)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.23894079] Gram-positive bacteria : Staphylococcus aureus (ATCC 29213)(MIC>40 μM);##Gram-negative bacteria : Escherichia coli (ATCC 25922)(MIC=10 μM)
Hemolytic Activity[Ref.23894079] MHC10>1280 μM against human red blood cells
Cytotoxicity[Ref.23894079] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23894079

Physicochemical Properties

Residues13
SequenceFKRQVQRIKDFLR
Molecular Weight1734.057
Grand Average of Hydropathy-1.054
Isoelectric Point11.723
Charge at pH 7.43.553
Secondary StructureHelix: 0.385, Turn: 0.000, Sheet: 0.077
Instability Index34.246
Aromaticity0.154

Similar Structure Search

Candidates based on structure

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