Basic Information

IDDRAMP21342
SequenceFLGALWNPAKSVF
Length13
Name[Pro]8-VmCT1-NH2 (Derived from VmCT1)
Sourcesynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=12.5 μmol/L), Bacillus subtilis ATCC 6633 (MIC=50 μmol/L);##Gram-negative bacteria: Serratia marcescens ATCC 4112 (MIC=12.5 μmol/L);##Fungi: Candida tropicalis IOC 4560 (MIC=50 μmol/L)
Hemolytic Activity[Ref.31212183] 0% hemolysis at 100 μmol/L for human red blood cells
Cytotoxicity[Ref.31212183] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID31212183

Physicochemical Properties

Residues13
SequenceFLGALWNPAKSVF
Molecular Weight1449.694
Grand Average of Hydropathy0.762
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.462, Turn: 0.308, Sheet: 0.308
Instability Index43.008
Aromaticity0.231

Similar Structure Search

Candidates based on structure

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