Basic Information

IDDRAMP21430
SequenceKKKLAFA
Length7
Namepeptide 7 (Derived from B1)
Sourcesynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.30842436] Gram-positive bacteria:MRSP C22963(MIC=8µg/ml), MSSA ATCC 29213(MIC=16µg/ml);##Gram-negative bacteria:Pseudomonas aeruginosa(MIC=16µg/ml)
Hemolytic Activity[Ref.30842436] EC10=8μM, EC50=140μM, 55% hemolysis at 150 µM against human red blood cells
Cytotoxicity[Ref.30842436] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID30842436

Physicochemical Properties

Residues7
SequenceKKKLAFA
Molecular Weight805.019
Grand Average of Hydropathy-0.214
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.286, Turn: 0.000, Sheet: 0.429
Instability Index-3.557
Aromaticity0.143

Similar Structure Search

Candidates based on structure

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