| ID | DRAMP21442 |
|---|---|
| Sequence | afalKKK |
| Length | 7 |
| Name | peptide 19 (Derived from B1) |
| Source | synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | [Ref.30842436] Gram-positive bacteria:MRSP C22963(MIC=16µg/ml), MSSA ATCC 29213(MIC=32µg/ml);##Gram-negative bacteria:Pseudomonas aeruginosa(MIC>64µg/ml) |
| Hemolytic Activity | [Ref.30842436] < 8% hemolysis at 150 µM against human red blood cells |
| Cytotoxicity | [Ref.30842436] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 30842436 |
Physicochemical Properties
| Residues | 7 |
|---|---|
| Sequence | afalKKK |
| Molecular Weight | 805.019 |
| Grand Average of Hydropathy | -0.214 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.6 |
| Secondary Structure | Helix: 0.286, Turn: 0.000, Sheet: 0.429 |
| Instability Index | -3.557 |
| Aromaticity | 0.143 |