Basic Information
| ID | DRAMP29094 |
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| Sequence | GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV |
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| Length | 36 |
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| Name | Turgencin A |
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| Source | Synoicum turgens |
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| Activity | Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-,Anti-cancer |
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| Pathogen | [Ref.32751755]Gram-positive bacteria:Bacillus megaterium(MIC=0.5 µg/mL); Bacillus subtilis(MIC=1.5 µg/mL); Corynebacterium glutamicum(MIC=1.5 µg/mL); Micrococcus luteus(MIC=8.0 µg/mL); Staphylococcus aureus(MIC=23.3 µg/mL);##Gram-negative bacteria:Escherichia coli(MIC=3.0 µg/mL); Pseudomonas aeruginosa(MIC=5.9 µg/mL);##Fungi: Rhodotorula sp(MIC=23.2 µg/mL);Aurobasidium pollulans(MIC=92.6 µg/mL); Candida albicans(MIC=46.3 µg/mL).##[Ref.31940927]Cancer:Human melanoma A2058(IC50=1.4 μM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.31940927]Cytotoxicity: Human fibroblasts MRC-5(IC50=4.8 μM). |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
C0HLN5 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 32751755, 31940927 |
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