| ID | DRAMP29096 |
|---|---|
| Sequence | GLPGPLGPAGPK |
| Length | 12 |
| Name | Collagencin |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.27038545]32.2% growth inhibition on Listeria innocua HPB29 at 235 µM; 31% growth inhibition on Lactococcus lactis ATCC 11454 at 235 µM ; 32.2% growth inhibition on Carnobacterium divergens M35 at 235 µM; 67% growth inhibition on Staphylococcus aureus ATCC 6538 at 235 µM; 62% growth inhibition on Streptococcus pyogenes ATCC19615 at 235 µM; 64% growth inhibition on Escherichia coli MC4100 at 235 µM; Escherichia coli O157:H7(NA); Aeromonas hydrophila ATCC 7966(NA); Pseudomonas aeruginosa ATCC 27853(NA). |
| Hemolytic Activity | [Ref.27038545]non-toxic to horse erythrocytes up to 470 μM; 25% hemolysis against horse erythrocytes at 940 µM. |
| Cytotoxicity | [Ref.27038545]No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | S4R4C8, S4R4C7, S4R4C5 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 27038545 |
Physicochemical Properties
| Residues | 12 |
|---|---|
| Sequence | GLPGPLGPAGPK |
| Molecular Weight | 1060.247 |
| Grand Average of Hydropathy | -0.208 |
| Isoelectric Point | 8.75 |
| Charge at pH 7.4 | 0.555 |
| Secondary Structure | Helix: 0.167, Turn: 0.667, Sheet: 0.250 |
| Instability Index | 41.267 |
| Aromaticity | 0 |
