Basic Information

IDdbAMP10636
SequenceRPWAGNGSVHRYTVLSPRLKTQ
Length22
NamePAM2 &&Ornithorhynchus anatinus&&Cathelicidin PAM2
SourceOrnithorhynchus anatinus
ActivityAntibacterial
PathogenStreptococcus uberis (MIC=0.51µM)&&Streptococcus pyogenes ATCC 19615 (MIC=0.83µM)&&Staphylococcus aureus ATCC 25923 (MIC=2.42µM)&&Salmonella enterica ATCC 14028 (MIC=1.11µM)&&Pseudomonas aeruginosa ATCC 27853 (MIC=0.73µM)&&Escherichia coli DH5alpha (MIC=0
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21912615

Physicochemical Properties

Residues22
SequenceRPWAGNGSVHRYTVLSPRLKTQ
Molecular Weight2523.849
Grand Average of Hydropathy-0.864
Isoelectric Point11.723
Charge at pH 7.43.589
Secondary StructureHelix: 0.273, Turn: 0.318, Sheet: 0.136
Instability Index1.441
Aromaticity0.091

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