Basic Information

IDdbAMP23186
SequenceGFFALIPKIISSPLFKTLLSAV
Length22
Name[D]-P7L18,19-Par[1-22]&&Par[1-22]&&Pardaxin P-4 (1-22)&&Des-(23-33)-pardaxin-[NH(CH2)2NH2]2&&Des-(23-33)-pardaxin
Source
ActivityAntibacterial
PathogenSalmonella typhimurium LT2 (MIC=>100µM)&&RBCs Source of Human (>100% hemolysis at 10µM)&&RBCs Source of Human (<20% hemolysis at 50µM)&&RBCs Source of Human (22% hemolysis at 50µM)&&RBCs Source of Human (1% hemolysis at 50µM)&&Pseudomonas aeruginosa ATCC
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8620888, 8620888, 9914515, 9914515

Physicochemical Properties

Residues22
SequenceGFFALIPKIISSPLFKTLLSAV
Molecular Weight2362.889
Grand Average of Hydropathy1.382
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.500, Turn: 0.273, Sheet: 0.273
Instability Index26.273
Aromaticity0.136

Similar Structure Search

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