Basic Information

IDDRAMP00036
SequenceITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK
Length34
NameNisin A (Bacteriocin; Preclinical)
SourceLactococcus lactis subsp. lactis (Streptococcus lactis) (Gram-positive bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Enterococcus, Lactobacillus, Lactococcus, Leuconostoc, Listeria, clostridium.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P13068
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID3141403, 5131162, 1575686

Physicochemical Properties

Residues34
SequenceITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK
Molecular Weight3498.192
Grand Average of Hydropathy0.415
Isoelectric Point8.781
Charge at pH 7.42.501
Secondary StructureHelix: 0.176, Turn: 0.265, Sheet: 0.176
Instability Index27.518
Aromaticity0

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