Basic Information

IDDRAMP00163
SequenceGWVACVGACGTVCLASGGVGTEFAAASYFL
Length30
NameThuricin CDdbeta (Trn-beta; one peptide of Thuricin CD; Bacteriocin)
SourceBacillus thuringiensis DPC 6431 (Gram-positive bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Clinical Clostridium difficile isolates (MIC in the range of nM) and Listeria monocytogenes, Lactobacillus fermentum.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot F5AT06
PDB 2LA0
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20435915, 21526839

Physicochemical Properties

Residues30
SequenceGWVACVGACGTVCLASGGVGTEFAAASYFL
Molecular Weight2868.266
Grand Average of Hydropathy1.24
Isoelectric Point4.05
Charge at pH 7.4-1.517
Secondary StructureHelix: 0.333, Turn: 0.267, Sheet: 0.300
Instability Index40.533
Aromaticity0.133

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