Basic Information

IDDRAMP00276
SequenceYSYKKIDCGGACAARCRLSSRPRLCNRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP
Length66
NameSnakin-2 (StSN2; Cys-rich; Plant defensin)
SourceSolanum tuberosum (Potato)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacteria: Clavibacter michiganensis (EC50=4 µM), Ralstonia solanacearum (EC50=15 µM).##Fungi: pathogens Rhizobium meliloti (EC50=8 µM), Botrytis cinerea (EC50=2 µM), Fusarium solani (EC50=2 µM), Fusarium culmorum (EC50=2 µM), Fusarium oxysporum f.sp. conglutinans (EC50=10 µM), Fusarium oxysporum f.sp.lycopersici (EC50=20 µM), Plectosphaerella cucumerina (EC50=10 µM), Colletotrichum graminicola (EC50=10 µM), Colletotrichum lagenarium (EC50=10 µM), Bipolaris maydis (EC50=20 µM), Aspergillus flavus (EC50=20 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q93X17, A1YN11, Q948Z5
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11891250

Physicochemical Properties

Residues66
SequenceYSYKKIDCGGACAARCRLSSRPRLCNRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP
Molecular Weight7037.112
Grand Average of Hydropathy-0.498
Isoelectric Point9.164
Charge at pH 7.48.284
Secondary StructureHelix: 0.121, Turn: 0.303, Sheet: 0.152
Instability Index46.055
Aromaticity0.045

Similar Structure Search

Candidates based on structure

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