Basic Information

IDDRAMP00977
SequenceVGECVRGRCPSGMCCSQFGYCGKGPKYCGR
Length30
NameAntimicrobial peptide 2 (AC-AMP2; Plant defensin)
SourceAmaranthus caudatus (Love-lies-bleeding) (Inca-wheat)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacteria: Bacillus megaterium (IC50=40 µg/ml), Sarcina lutea (IC50=250 µg/ml).##Fungi: Alternaria brassicola (IC50=7 µg/ml), Ascochyta pisi (IC50=8 µg/ml), Botrytis cinera (IC50=10 µg/ml), Colletotrichum lindemuthianum (IC50=8 µg/ml), Fusarium culmorum (IC50=2 µg/ml), Trichoderma hamatum (IC50=7 µg/ml), Verticillium dahliae (IC50=6 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P27275
PDB 1MMC, 1ZNT, 1ZUV, 1ZWU
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1567877, 8627629, 9176817

Physicochemical Properties

Residues30
SequenceVGECVRGRCPSGMCCSQFGYCGKGPKYCGR
Molecular Weight3189.74
Grand Average of Hydropathy-0.347
Isoelectric Point8.92
Charge at pH 7.43.367
Secondary StructureHelix: 0.167, Turn: 0.367, Sheet: 0.067
Instability Index21.883
Aromaticity0.1

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.