Basic Information

IDDRAMP00976
SequenceVGECVRGRCPSGMCCSQFGYCGKGPKYCG
Length29
NameAntimicrobial peptide 1 (AC-AMP1; Plant defensin)
SourceAmaranthus caudatus (Love-lies-bleeding) (Inca-wheat)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacteria: Bacillus megaterium (IC50=40 µg/ml), Sarcina lutea (IC50=250 µg/ml).##Fungi: Alternaria brassicola (IC50=7 µg/ml), Ascochyta pisi (IC50=8 µg/ml), Botrytis cinera (IC50=10 µg/ml), Colletotrichum lindemuthianum (IC50=8 µg/ml), Fusarium culmorum (IC50=2 µg/ml), Trichoderma hamatum (IC50=7 µg/ml), Verticillium dahliae (IC50=6 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P27275
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1567877, 9176817

Physicochemical Properties

Residues29
SequenceVGECVRGRCPSGMCCSQFGYCGKGPKYCG
Molecular Weight3033.554
Grand Average of Hydropathy-0.203
Isoelectric Point8.66
Charge at pH 7.42.367
Secondary StructureHelix: 0.172, Turn: 0.379, Sheet: 0.069
Instability Index22.293
Aromaticity0.103

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