| ID | DRAMP00985 |
|---|---|
| Sequence | QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCRS |
| Length | 41 |
| Name | Pn-AMP1 (PnAMP1; Plant defensin) |
| Source | Ipomoea nil (Japanese morning glory) (Pharbitis nil) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Antifungal |
| Pathogen | Gram-positive Bacterium: Bacillus subtilis (IC50=38 µg/ml).##Fungi (Medium A, Medium A+): Botrytis cinerea (IC50=16, 150 µg/ml), Colletotrichum langenarium (IC50=10, >200 µg/ml), Sclerotinia sclerotiorum (IC50=11, >200 µg/ml), Fusarium oxysporum (IC50=10, >200 µg/ml), Rhizoctonia solani (IC50=26, >200 µg/ml), Phytophthora capsici (IC50=5, 130 µg/ml), Phytophthora parasitica (IC50=3, 90 µg/ml), Saccharomyces cerevisiae (IC50=14, >200 µg/ml).##NOTE! Medium A+ = Medium A supplemented with 5 mM CaCl2. |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P81591 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 9507071 |
Physicochemical Properties
| Residues | 41 |
|---|---|
| Sequence | QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCRS |
| Molecular Weight | 4325.811 |
| Grand Average of Hydropathy | -0.52 |
| Isoelectric Point | 8.764 |
| Charge at pH 7.4 | 3.356 |
| Secondary Structure | Helix: 0.122, Turn: 0.341, Sheet: 0.122 |
| Instability Index | 35.722 |
| Aromaticity | 0.073 |