| ID | DRAMP00986 |
|---|---|
| Sequence | QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCR |
| Length | 40 |
| Name | Pn-AMP2 (PnAMP2; Plant defensin) |
| Source | Ipomoea nil (Japanese morning glory) (Pharbitis nil) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Antifungal |
| Pathogen | Gram-positive bacterium: Bacillus subtilis (IC50=20 µg/ml).##Fungi (Medium A, Medium A+): Botrytis cinerea (IC50=2, 95 µg/ml), Colletotrichum langenarium (IC50=4, ND µg/ml), Sclerotinia sclerotiorum (IC50=3, >200 µg/ml), Fusarium oxysporum (IC50=2.5, >200 µg/ml), Rhizoctonia solani (IC50=75, >200 µg/ml), Phytophthora capsici (IC50=0.6, 150 µg/ml), Phytophthora parasitica (IC50=2, >200 µg/ml), Pythium spp. (IC50=2.5, ND µg/ml), Saccharomyces cerevisiae (IC50=8, >200 µg/ml).##NOTE! Medium A+ = Medium A supplemented with 5 mM CaCl2. |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P81591 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 9507071 |
Physicochemical Properties
| Residues | 40 |
|---|---|
| Sequence | QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCR |
| Molecular Weight | 4238.734 |
| Grand Average of Hydropathy | -0.513 |
| Isoelectric Point | 8.764 |
| Charge at pH 7.4 | 3.356 |
| Secondary Structure | Helix: 0.125, Turn: 0.325, Sheet: 0.125 |
| Instability Index | 25.38 |
| Aromaticity | 0.075 |