Basic Information

IDDRAMP00987
SequenceQQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCG
Length45
NameEe-CBPb (Hevein-like antimicrobial peptide; Plants)
SourceEuonymus europaeus (European spindle tree)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenFungi: Alternaria brassicicola (IC50=3 µg/ml), Botrytis cinerea (IC50=1 µg/ml), Fusarium culmorum (IC50=3 µg/ml), Fusarium oxysporum f.sp.cubense (IC50=15 µg/ml), Fusarium oxysporum f.sp. Matthiolae (IC50=5 µg/ml), Mycosphaerella eumusae (IC50=6 µg/ml), Neurospora crassa (IC50=2 µg/ml), Phoma exigua (IC50=33 µg/ml), Phytophthora cryptogea (IC50=25 µg/ml), Pythium ultimum (IC50=33 µg/ml), Rhizoctonia solani (IC50=25 µg/ml).##Gram-positive bacteria: Bacillus megaterium (IC50=2 µg/ml), Sarcina lutea (IC50=7 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15048569, 12387889

Physicochemical Properties

Residues45
SequenceQQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCG
Molecular Weight5019.568
Grand Average of Hydropathy-1.038
Isoelectric Point8.8
Charge at pH 7.44.306
Secondary StructureHelix: 0.089, Turn: 0.289, Sheet: 0.089
Instability Index57.942
Aromaticity0.067

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Candidates based on structure

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