Basic Information

IDDRAMP00981
SequenceAQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGCR
Length45
NameAntimicrobial peptide 1b (WAMP-1b; Plant defensin)
SourceTriticum kiharae (wheat)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenFungi: Bipolaris sorokiniana (IC50=5 µg/ml), Botrytis cinerea (IC50=20 µg/ml), Fusarium oxysporum (IC50=5 µg/ml), F. solani (IC50=5 µg/ml), F. verticillioides (IC50=30 µg/ml), Neurospora crassa (IC50=10 µg/ml);##Gram-positive bacterium: Clavibacter michiganensis (1.3cm inhibition for 2.5 µg/50µl);##Gram-negative bacteria: Erwinia carotovora (1.1cm for 2.5 µg/50µl), Pseudomonas syringae (0.9cm for 2.5 µg/50µl).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P85966
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19583772, 16269343

Physicochemical Properties

Residues45
SequenceAQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGCR
Molecular Weight4601.202
Grand Average of Hydropathy-0.442
Isoelectric Point8.617
Charge at pH 7.43.354
Secondary StructureHelix: 0.089, Turn: 0.311, Sheet: 0.133
Instability Index24.316
Aromaticity0.067

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Candidates based on structure

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