Basic Information

IDDRAMP00993
SequenceQAGGQTCPGGICCSQWGYCGTTADYCSPNNNCQSNCWASG
Length40
NameWjAMP-1 (C-terminal domain of hevein; Plant defensin)
SourceWasabia japonica L. (Wasabi plant) (Wasabia japonica)
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli (IC50=27.5 µg/ml), Pseudomonas cichorii (IC50=13.8 µg/ml), Pseudomonas glumae (IC50=20 µg/ml), Pseudomonas plantarii (IC50=22.5 µg/ml), Agrobacterium tumefaciens (IC50=12.5 µg/ml).##Fungi: Alternaria alternata (IC50=5.8 µg/ml), Botrytis cinerea (IC50=15 µg/ml), Fusarium solani (IC50=8.4 µg/ml), Magnaporte grisea (IC50=80 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12668776

Physicochemical Properties

Residues40
SequenceQAGGQTCPGGICCSQWGYCGTTADYCSPNNNCQSNCWASG
Molecular Weight4094.398
Grand Average of Hydropathy-0.495
Isoelectric Point4.05
Charge at pH 7.4-1.619
Secondary StructureHelix: 0.125, Turn: 0.425, Sheet: 0.075
Instability Index35.275
Aromaticity0.1

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