Basic Information

IDDRAMP01126
SequenceILGPVISKIGGVLGGLLKNL
Length20
NameMaximin-H4 (Toads, amphibians, animals)
SourceBombina maxima (Giant fire-bellied toad) (Chinese red belly toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.11835991] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=12 μg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=6 μg/ml), Bacillus pyocyaneus CMCCB 1010 (MIC=12 μg/ml).##Yeast: Candida albicans ATCC 2002 (MIC=6 μg/ml).
Hemolytic Activity[Ref:11835991]90–100% hemolytic activity at 50 μg/ml against rabbit red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83084, Q58T61, Q58T60
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15770703, 11835991

Physicochemical Properties

Residues20
SequenceILGPVISKIGGVLGGLLKNL
Molecular Weight1961.434
Grand Average of Hydropathy1.26
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.500, Turn: 0.400, Sheet: 0.250
Instability Index32.61
Aromaticity0

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.